September 9, 2025
Low energy, mood swings, and a declining sex drive can be signs that may point to low testosterone levels. For many men, the answer lies in Testosterone Replacement Therapy (TRT).
Testosterone Replacement Therapy (TRT) involves delivering synthetic or bioidentical testosterone to individuals whose bodies produce insufficient levels of the hormone, known as hypogonadism. Low testosterone can cause fatigue, low libido, loss of muscle mass, mood changes, and more.
Reputable guidelines recommend a total testosterone level below 3.0 ng/mL on two separate early-morning tests for the diagnosis of hypogonadism.
TRT treatment may be appropriate if you experience the below symptoms:
And your testosterone level—confirmed by two morning blood tests—is consistently below the normal level. Patients who are considering fertility should be evaluated carefully, as it can suppress sperm production.
There is no strict standard for testosterone levels. For active men, even 4–5 ng/ml may not be enough to feel well. For older individuals who are less physically and sexually active, these levels may be sufficient. That’s why our management is always tailored to the specific needs of each patient.
One of the advantages of Testosterone Replacement Therapy is the flexibility it offers—there isn’t a “one-size-fits-all” solution. The method of delivery depend on your lifestyle, health goals, and how your body responds to treatment. At Reem Hospital, we provide several safe and effective TRT options:
At Reem Hospital, our urologists carefully assess your health status, testosterone levels, and lifestyle preferences to recommend the option that provides the best balance of safety, convenience, and effectiveness.
Patients often experience improvements within weeks:
However, responses can differ—regular monitoring helps personalize optimal dosing and progress.
Testosterone Replacement Therapy requires responsible oversight:
Close follow-up ensures both safety and effectiveness.
| Condition | Implication |
| Prostate Cancer | For years, there was concern that Testosterone Replacement Therapy could fuel prostate cancer growth. Current research suggests that it does not cause prostate cancer, but it may accelerate growth in men with existing, undiagnosed prostate cancer. That’s why men undergoing treatment should have regular PSA tests and prostate evaluations. At Reem Hospital, patients are screened before and closely monitored during therapy for safety. |
| Fertility | One of the most important considerations with Testosterone Replacement Therapy is its impact on fertility. TRT can suppress natural testosterone production, which in turn lowers sperm count. This makes it unsuitable for men actively trying to conceive. Alternatives like clomiphene citrate, hCG therapy, or selective estrogen receptor modulators (SERMs) may be considered instead. Our specialists at Reem Hospital guide men toward the safest option based on family planning goals. |
| Erectile Dysfunction (ED) | While low testosterone can contribute to erectile dysfunction, not all ED is hormone-related. It can significantly improve libido and sexual function in men with hypogonadism, but men with vascular or psychological causes of ED may need additional treatments. |
| Estrogen Blockers | As testosterone levels rise during Testosterone Replacement Therapy (TRT), some men may convert excess testosterone into estrogen (via aromatization), leading to side effects like breast tenderness, water retention, or mood swings. In these cases, doctors may prescribe aromatase inhibitors (estrogen blockers) to maintain balance. However, these are used cautiously since too little estrogen can negatively affect bone and heart health. |
| Heart Disease | The relationship between TRT and heart disease has been debated. Some studies show TRT may decrease cardiovascular risk factors like body fat, insulin resistance, and cholesterol. Others highlight potential risks like blood thickening (polycythemia) and increased clot risk. At Reem Hospital, patients with pre-existing heart conditions undergo careful screening and monitoring before starting TRT. |
| Weight Loss | TRT can help men with low testosterone reduce fat mass and increase lean muscle mass. Improved energy and motivation often lead to more physical activity, which supports weight management. While TRT alone isn’t a “weight-loss treatment,” combined with exercise and nutrition, it can be a powerful tool for restoring a healthier body composition. |
| High Blood Pressure | TRT may slightly increase blood pressure in some men, partly due to increased red blood cell count and water retention. Monitoring blood pressure before and during treatment is essential. Lifestyle measures—diet, exercise, stress reduction—remain key, and any rise in blood pressure is addressed promptly. |
| Hair Loss | Some men worry that TRT will worsen hair thinning. While testosterone itself does not directly cause baldness, its conversion into dihydrotestosterone (DHT) can accelerate genetic male-pattern hair loss in men who are predisposed. Since DHT is the biologically active form of testosterone, combining TRT with finasteride (a DHT blocker) may not always make sense, as it could counteract some of the intended benefits of therapy. |
Pros
Cons
The dosage is not one-size-fits-all. It is tailored based on:
Guidance closely follows international practice, ensuring patients receive effective yet safe dosing for long-term health. To get a personalized treatment, you will have to consult a urologist.
In today’s fast-paced world, hormonal imbalance can undermine energy, mood, and intimacy. When guided responsibly—can rekindle physical vitality, mental sharpness, and emotional confidence.
At Reem Hospital, our expert urologists commitment to excellence, safety, and individual care sets us apart. From your initial tests to personalized TRT plans, constant monitoring, and expert follow-ups—you’re supported every step of the way.
Reference: DOH
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